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URL of this page: https://medlineplus.gov/druginfo/meds/a601206.html

Cefuroxime

pronounced as (se fyoor ox' eem)

Why is this medication prescribed?

Cefuroxime is used to treat certain infections caused by bacteriaand Lyme disease (an infection spead by ticks). It is also used to treat gonorrhea (a sexually transmitted disease).. Cefuroxime is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria.

Antibiotics such as cefuroxime will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

How should this medicine be used?

Cefuroxime comes as a tablet to take by mouth. It is usually taken every 12 hours for 5-20 days, depending on the condition being treated. To treat gonorrhea, cefuroxime is taken as a single dose. Take with or without food at around the same times every day.  Swallow tablets whole. Because the crushed tablet has a strong bitter taste, the tablet should not be crushed.Take cefuroxime exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

You should begin to feel better during the first few days of treatment with cefuroxime. If your symptoms do not improve or get worse, call your doctor.

Take cefuroxime until you finish the prescription, even if you feel better. If you stop taking cefuroxime too soon or skip doses, your infection may not be completely treated, and the bacteria may become resistant to antibiotics.

Other uses for this medicine

Cefuroxime is also sometimes used to treat pneumonia. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking cefuroxime,

  • tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
  • you should know that some medications should not be taken with cefuroxime. Other medications may cause dosing changes or extra monitoring when taken with cefuroxime. Make sure you have discussed any medications you are currently taking or plan to take before starting cefuroxime with your doctor and pharmacist. Before starting, stopping, or changing any medications while taking cefuroxime, please get the advice of your doctor or pharmacist.
  • you should know that the following nonprescription products may interact with cefuroxime: cimetidine, famotidine, omeprazole, ranitidine. Be sure to let your doctor and pharmacist know that you are taking these medications before you start taking cefuroxime. Do not start any of these medications while taking cefuroxime without discussing with your healthcare provider.
  • you should know that if you are taking antacids that contain magnesium or aluminum, take them at least 1 hour before or 2 hours after cefuroxime.
  • tell your doctor if you have or have ever had gastrointestinal disease (GI; affecting the stomach or intestines), especially colitis (condition that causes swelling in the lining of the colon), or kidney or liver disease.
  • you should know that cefuroxime may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, and injections). You will need to use another method of contraception to prevent pregnancy while taking cefuroxime. Talk to your doctor about other ways to prevent pregnancy while you are taking this medication.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefuroxime, call your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cefuroxime may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea, vomiting, diarrhea

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

  • rash, itching, hives; difficulty breathing or swallowing; wheezing; swelling of the face, throat, tongue, lips, or eyes
  • watery or bloody stools, stomach cramps, or fever during treatment or for up to two or more months after stopping treatment
  • a return of fever, sore throat, chills, or other signs of infection

Cefuroxime may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom).

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • seizures

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to cefuroxime.

If you are diabetic and test your urine for sugar, use Clinistix or TesTape (not Clinitest) to test your urine while taking this medication. If you test your blood for sugar, check with your doctor or pharmacist to recommend the best product to use while taking this medication.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finishthe cefuroxime, call your doctor.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

Brand names

  • Ceftin®
Last Revised - 06/15/2026